For permanent connections, I've often just usedsoldered wires into pads - you may have to make a single pin component (module/footprint) for this, depending on your CAD system.
For less permanent connections, there are several styles of PC-mounted screw or spring terminal blocks that will take single wires.
Unless you have suitable tooling to make the mating cables, I would avoid the .025" post headers, but there are other connectors that can be mounted directly to a PC board.