I'm working on the parts list for a number of designs for low-voltage (24 VDC) industrial circuits that have no special safety requirements: so long as they don't catch fire no one could be hurt nor property damaged. But they will be used in environments where replacement is expensive, as they are sealed into a more expensive larger unit, and they are in a remote location far away so flying an engineer there to do the refit is very expensive. So replacing a £10 unit might cost several thousand if it fails in service. If the best parts were 10% or 20% more expensive, for our number of units, it's easily much cheaper than a single failure in the field. (Ignoring for the present purposes downtime and reputational costs.) Edit to add: these units are exposed to weather, and the overwhelming majority of failures in the field are moisture ingress, a small amount of DOA. We have ten year failure rate data, and have good approaches for housing etc.
To maximise reliability I was thinking about increasing margins in general: closer tolerance components, thicker tracks on the PCB etc, extra headroom in the power supply, extra temperature range parts, longer soak test, and so on.
I don't have experience of automotive (nor aerospace, nuclear, medical etc) industries, but was considering using the best available parts, within reason.
As far as I've been able to find out, all the AEC Q100 (101, 200) ratings are about reducing the number of failed devices, but they should perform exactly the same.
Assuming cost margins are acceptable, and performance is within spec, is there ever a reason to prefer an ordinary-grade part over an equivalent automotive-grade one?
Edited to clarify: I'm trying to understand if there are any negatives at all to automotive-grade parts other than price.
Edited again to clarify: Our starting point is reputable manufacturer via reputable distributor, such as Microchip/ST/Vishay etc and Mouser/Digikey/Arrow etc. We are not looking at parts via Ebay or Alibaba. We haven't looked at milspec and aerospace parts because a) they don't appear to be available through our channels, and b) are assumed to be way out of the price we're working to. Hence this question is focussed on automotive grade which is easily available and has a premium of 10%-100% for the parts we're looking at.
For a concrete example ATMEGA328PB-ABTVAO versus ATmega328PB-AN. Same package, reel size, temperature range (-40C to +105C), automotive part is about 8.5% more expensive (whole reels, manufacturer's web site prices). It is given as having a more conservative voltage (2.7 V vs 1.8 V) and maximum clock (16 MHz vs 20 MHz). My understanding is it's from the identical design, but with better testing and more conservative promises in order to minimise, ideally to zero, the number of parts which go outside spec?
The automotive part's datasheet has only the following to say:
7. Automotive Quality Grade The devices have been manufactured according to the most stringent requirements of the international standard ISO/TS 16949. This data sheet contains limit values extracted from the results of extensive characterization (temperature and voltage). The quality and reliability have been verified during regular product qualification as per AEC-Q100 grade 2 (–40°C to +105°C). (Datasheet p20)
Edited to add: some commenters have said automotive grade has better certified temperature range; note that is not the case for this particular part, where both the industrial -N unit and the automotive part have the same temperature range. Which is why I'm asking about what exactly "automotive" might imply, in general.