There have been questions regarding connection of grounds of an isolated DC-DC converter. However I could not find anything that discusses whether the two grounds (when connected) should only be connected at one point.
I have connected the input and output returns of the isolated DC-DC converter using a jumper at a single point, and consequently created two split grounds on the bottom layer (as shown in the image of the layout). Is this advisable? Just to be clear, there are no other analog circuits on this board (ADC, DAC, etc), only the typical components that accompany a DC-DC converter: fuse, TVS diode, filtration caps, and LC filter.