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I have to amplify an analog signal 0 - 0.3v from a sensor to 0 - 2.5v which the XBee's analog input accepts and onlt have access to one 3.3v and gnd power supply rail(no negative rail). I've tried the 741 op amp but am getting problems with it and and it doesn't seem to work. If you could help me out with the circuit and the opamp chip that would fit best for this low power application. Thanks!

Update: So i've found a chip that is mostly designed for single supply use which is the TLV2472 and it does a great job doing this in our final circuit that we have built and tested. The datasheet and an application document we fount helped us build an amplifying circuit that worked for our application.

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    \$\begingroup\$ Yeah, the 741 doesn't work because it requires a minimum of +/- 10V supply rails. Search for rail to rail op amps. There are probably a dozen questions that could be considered duplicates of this one. \$\endgroup\$ – Matt Young Jan 20 '16 at 20:02
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    \$\begingroup\$ I wish that the 741 would have been discontinued years & years ago. There are sooo many better opamps now and the number of new/amateur EEs who get stuck because they're trying to use that old thing in 'new' low voltage circuits ... \$\endgroup\$ – brhans Jan 20 '16 at 20:10
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Use a rail to rail opamp that can run from 3.3 V. Many of the Micropchip MCPxxx line, for example, can do what you want.

Run the opamp in positive gain configuration with ground as the reference. The gain needs to be about 8. All you should need is the opamp with its bypass cap, and two resistors.

As Andy pointed out, even "rail to rail" opamps might not do what you want within a few 10s of mV of either rail. Check the datasheet.

If this is a problem, you can use a small charge pump to make a small negative voltage. There are charge pump ICs for this purpose, but if you have a microcontroller with a spare pin this can be even simpler. I have used the clock output feature of a micro a few times just to run a charge pump from. If you only need a few mA, you can run the charge pump directly from the clock out or PWM logic signal. All you need is two diodes and two caps. If you need a little more current, follow the logic signal with a NPN/PNP emitter follower pair. That will reduce the negative voltage magnitude by 1.4 V or so, but even with 3.3 V supply there is plenty left to get ground well past the rail region of a "rail to rail" opamp.

With a volt or two negative supply, you can sometimes use much cheaper opamps, which makes the charge pump option cheaper overall. For example, if you can use a LM324 if only you had a negative voltage, then quite likely the more expensive opamps that go to the negative rail will outweigh the few diodes and caps to make the charge pump.

As always, look at the opamp datasheet carefully. If the micro is running from 5 V and you are using the logic signal directly to drive the charge pump, you may actually be giving the opamp too much voltage. The opamps that get close to real rail to rail performance also tend to work over a limited supply range.

If you do use a charge pump, it would be a good idea to filter the charge pump output before it is applied to the opamp negative power input. A ferrite "chip inductor" in series followed by a 20 µF cap to ground should be enough.

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    \$\begingroup\$ (Not to Olin) Be aware that the bottom 20mV of the output will probably be dead to signal even wih a R2R op-amp. If you need fidelity below 20mV on the output then you'll need a negative rail. \$\endgroup\$ – Andy aka Jan 20 '16 at 22:59
  • \$\begingroup\$ @Andy: Good point. I've expanded my answer to discuss this. \$\endgroup\$ – Olin Lathrop Jan 21 '16 at 11:51

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