I have a PCB with two power rails, 5V and 12V, and two ground pours, GND-5V and GND-12V, respectively. The two ground pours are tied at one point (close to the connector). I'm powering a DAC off the 5V rail and buffering its output using an opamp that is also powered off the 5V rail. The output of the buffer is fed to the control pin of a DC-DC converter that is powered off the 12V rail. The datasheet for the DC-DC converter suggests a 0.1uF bypass capacitor for the control pin.
Should the return path of the bypass capacitor (shown as Cb in the image below) be GND-5V, as any spikes would be coming from the 5V rail, OR should it be GND-12V as that's the converter's return path? Note that the both the opamp and the DAC have bypass capacitors as well.