Does it matter whether you wear your anti-static wrist strap around your wrist or around your ankle?
It makes no difference where you connect the anti-static strap to your body.
The reason is that your body is much lower resistance between any two points than the strap is.
Also, most of the resistance between any two points on your skin is getting thru the skin at each point. You're just a bag of saltwater (electrically, anyway). The bag has a resistance of a few kΩ to a few 100 kΩ from the outside to the inside, but once inside, the saltwater effectively shorts everything together relative to the bag's resistance.
So the body adds negligible total resistance to the strap, and resistance between any two points on the body is largely independent of where on the body those two points are. It's really about how dry the skin is at the connection points, not where the connections are.
Electrically, it doesn't matter where it makes contact, with contact being the key word! I find however that it doesn't suit my workflow round either wrist or ankle.
If worn on my wrist, the trailing wire interferes with stuff on my bench. If worn on my ankle, it's a long way down to attach and detach, and being out of sight, it's easy to be working for a while at the bench and suddenly realise that I've not been grounded for the last few minutes. Notwithstanding that I am stronger than the popper holding it together, I can still fall over if I walk away from my bench without detaching it. If people come to talk to me from alternate sides, I can contrive to wrap it round the pillar of my revolving chair.
Fortunately my workplace is very tolerant of solutions that work, even if they are unconventional. I wear a gold chain at work, with an attached wire poking out through my shirt front. This is where I clip my grounding lead. It doesn't get in the way, it's easy to reach for on and off, and easy to see to remind me I've got it on, and not to tangle myself in it.
Just be sure that it is properly connected to whatever reference you have around.
The table/bench you work on should also be at the same potential, and if possible also use an anti static mat and chair.
All those does not need to be grounded, but they do need to be connected to the same potential. If ground is available ground them.
You probably do not even need the anti static wrist strap: grab your silicon/boards/whatever and let it sit for a while on your bench. After some time... voila', everything is at bench potential. If you also are at bench potential there is no harm in touching the device without wearing the strap.