I am trying to engineer a device to separate red blood cells from blood plasma in 100mmx1mm capillary tubes using the raspberry pi GPIO pin PWM feature and a piezoelectric actuator. The pulses generated by PWM will drive a piezoelectric actuator disk from Thor Labs using DC pulses (link: https://www.thorlabs.com/drawings/e156ef3a59a932ba-124DF929-CB86-F6E9-8CA97377261D0DE2/PA25LEW-SpecSheet.pdf). The problem I face is that the raspberrypi GPIO pins only generate pulses around 3V, but I may need a pulse that is 20V to 150V @ up to 1 amp in order to drive the piezoelectric actuator. From my research, I believe I will need to link the GPIO output to a transistor that is capable of handling the load from a power source. I need suggestions on designs for such a high voltage circuit that wont blow up my raspberry pi or light my house on fire. The most useful circuit would be one that is hooked up to a variable resistor so I could modulate the voltage (would be dope if I could control that with the raspberry pi). Power supply recommendations would also be useful. Ideally I would be able to use the wall outlet as a power source.
The scope of this project is to replicate the results of these papers: “Development of Micro Particles Separation Device with Piezo-Ceramic Vibrator” Katsutoshi Ooe, Toshio Fukuda
Transport and Concentration of Blood in Capillary Tube using Flexural Acoustic Wavw” Eun-Sun Kim, In-Kag Hwang
“Long –range Particle Manipulation in a Micro-Capillary tube using a flexural acoustic wave” Eun-Sun Kim, In-Kag Hwang
I intend to generate a single antinode in the center of the capillary tube to concentrate the RBC’s and give me a clear view of the blood plasma that I can take a picture of using a raspberry pi camera with low focal length lens.
Any help is much appreciated!