It might be difficult to find a one all solution that is easy to use. Analog simulations typically use SPICE code, and that means finding the files from each manufacturer and integrating them into a SPICE simulation
There are few mixed digital solutions, proteus is one of them and can simulate PIC's and SPICE code.. You'll most likely need to find models for each analog component you want to simulate.
If time is your interest, it's usually best to substitute a PWL file that represents the digital inputs and only simulate the analog sections in a spice programs such as LT spice. A PWL voltages is a a list of times and voltages that you can replicate digital signals with. This is how you would do this in LT spice
The other problem is there is not a spice file readily available from the manufacturer for the NCE0140KA, so a way to get around this is to find an equivalent mosfet with a spice file and simulate that, or to contact the manufacturer and ask for one.
Its usually best to simulate only after there is a proper design, and use simulation for verification. It's also a good practice to simulate only the sections of the design that aren't fully understood and are hard to work out on paper.