If I have an 8-bit high-speed interface say at 1GHz talking to memory and I want to do interface testing, I can send patterns like AA/55/00/FF.
When I send a pattern like 55 i.e 01010101, every even bit sees a rise transition.
In the case of AA - 10101010, every odd bit sees a rise transition.
In short, I can exercise maximum toggle per bit to see rise/fall delay effects per bit using a pattern like A5 or 5A.
From an electrical perspective does the use of FF and 00 patterns give any additional benefit?