Ignore the ground symbol for the moment.
From A to D, you will have 6 volts. That is, if you put the negative terminal (black) of the voltmeter on point D (the minus pole of the battery) and the positive terminal (red) of the voltmeter on point A (the positive pole of the battery) then you will measure 6 volts.
The current is 6 volts divided by the sum of all the resistances : \$I = \frac {6}{150 + 75 + 225} = \frac {6}{450}\$
From \$I\$, you can calculate the voltage drop across each resistor.
- From A to B is \$ 150 \times I\$
- From B to C is \$ 75 \times I \$
- From C to D is \$ 225 \times I\$
If you assume that D is at zero volts, then you get the following voltages:
- D = 0
- C = 0 + \$ 225 \times I\$
- B = 0 + \$ 225 \times I\$ + \$ 75 \times I \$
- A = 0 + \$ 225 \times I\$ + \$ 75 \times I \$ + \$ 150 \times I\$
That's if you ignore the ground symbol.
Putting the ground symbol at point C means that you should measure all voltages relative to point C - point C is your "zero volts" point rather than point D.
That is, put the negative terminal (black) of the voltmeter on point C and the positive terminal (red) of the voltmeter on point A to make your measurement. The voltages relative to the battery minus pole don't change, but the voltages you measure will be different because you aren't measuring against the minus pole of the battery.
If you assume that C is at zero volts, then you get the following voltages:
- C = 0
- B = 0 + \$ 75 \times I \$
- A = \$ 75 \times I \$ + \$ 150 \times I\$
- D = 0 - \$ 225 \times I\$
The difference between voltage A and voltage D is always 6V. The voltages must all add up to the same 6 volts that your battery provides, but you can measure them relative to any point you like.
You could put the ground symbol on point A, and measure the other points relative to point A. The total will be the same, but you'll have different voltages.
This is the point where you should get out a multimeter, some resistors, and a battery (or power supply.)
Assemble a few examples like the circuit you were given, and measure the voltages using different "ground points." Use the minus pole of the battery, then the plus pole of the battery, then some point in between.
The sum will always be your battery voltage, though the measured voltages will depend on the resistor values.
It sounds horribly complicated, but a few minutes with a voltmeter and some resistors should make it much clearer.