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I think I connected the Data wires from the FT232RL to the USB Isolator ADUM3160BRWZ upside down.

enter image description here

I just want to confirm this, Data - of the one should be connected to Data + of the other ?

Datasheet page 7 of the isolator:

Datasheet

NOTE: The FT232RL is not the issue here. The wiring from the MCU to the FT232 works fine, I connected them to my computer and communicates. When I added the isolator between them and connected the computer, It could not detect any device on the usb port. I also tried to connect the usb data cables the other way in case I messed the USB cable, but this did not work either.

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The picture is correct. M means minus (-) and P means plus (+) so this is not the issue.

Data+ must be connected to Data+, and Data- must be connected to Data-.

It seems that the downstream and upstream ports are the wrong way though.

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  • \$\begingroup\$ You mean that the microcontroller should be on the "right side" of the Isolator? (To the DD- and DD+ side?) \$\endgroup\$
    – Christianidis Vasilis
    Commented Mar 24, 2021 at 11:32
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    \$\begingroup\$ PC is upstream, FT232 is downstream \$\endgroup\$
    – Justme
    Commented Mar 24, 2021 at 11:41

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