In ASIC design (and probably FPGA design as well), internal logic tri-state gates are to be avoided unless absolutely necessary. There are several reasons why that is the case, but the short version is that the rule keeps you from shooting yourself in the foot, and isn't really costing you area. Note that within a gate boundary, it's fine as long as the output is a standard CMOS output.

simulate this circuit – Schematic created using CircuitLab
The two inverters generating the inverted select signals are not shown for either schematic
Comparing these two topologies, the tri-state topology provides significantly less propagation delay from your data inputs to your output. Not shown is the four NAND + four INV gates needed to generate the select signal for each individual tri-state gate. That's a total of 46 transistors for this topology, and two-ish gate delays from A->Y. There will be greater current consumption when switching between selected lines as there will be some shoot-through current on the tri-state node (e.g. from NOT1 to NOT3).
The fully static gate implementation adds the decoder into the data path. At this point, you could make a 4-input NAND to replace the output stage, but it's a bunch of trade-offs of whether you want 2 faster stages, or one slower 4-input gate stage. As drawn, this comes to 42 transistors, just a bit smaller. The S to Y timing will probably be a bit faster and will not short out two gates.
Neither design will be fun to lay out well as a single gate in an ASIC library.
Answering the questions
- The timing differences depend on use cases - Faster A->Y time would favor the tri-state gate, while faster S->Y time would favor the static gate. The overall difference is not very large.
- The static design is probably a bit smaller at 42 transistors compared to the 46 for the tri-state gate as drawn.
- The tri-state design has shoot-through current between tri-state inverters when the select line changes. Neither designs are glitch free.
Overall, from an ASIC perspective, I would probably pick the tri-state design most of the time. If you're in a FPGA, it doesn't matter either way (it gets handled by the LUT)