(1) Well, let us read the datasheet first: (1) TDA7575B 2 x 75W multifunction dual-bridge power amplifier with integrated digital diagnostics - ST https://www.st.com/resource/en/datasheet/tda7575b.pdf
(2) Then let us compare the datasheet's Fig 1 block diagram with your schematic. I forgot how to upload my comparison diagram to Imgur. So cheat by putting it as a quick and dirty answer.
(3) ST7575B is I2C 75W digital power amp, with two channel differential inputs, and two channels 1Ω output.
(4) If you are playing with single channel, I would suggest to short both IN1 and IN2 to signal ground.
(5) And if also want single channel output, Datasheet Section 5.5 also suggests to parallel the two speakers together.
(6) Second part of Section 5.5 also suggests to (a) float IN1, or (b) short to ground.