M3 has |Vds| > 300V |Vgs| = 10V
Protecting the load from V1 = -300V 100ms spike:
Does this diagram, with carefully picked components, look like it will do the job ? Hw do I select R1, D2 and D3 ?
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Answer edited since I mis-read the original schematic (Thought it was an NFET).
It may work, but presumably when the FET is on and Vin is 12V the source is also about 12V and the gate is zero. If the max Vgs is 10V you're exceeding that spec. You could put some resistance in series with the gate and use your diodes to clamp the max Vgs to <10V.