Yes, both of them are wires, and provide paths for electrons to flow, so they are the same thing. But you may be missing a subtlety: the purpose of a power rail is to carry power (= energy), and the purpose of a signal line is to carry information. That means when designing a power rail we are more concerned with things like voltage drop and heat dissipation; when designing a signal line we are more concerned with things like interference and reflections.
In the most basic cases, there is nothing to worry about and either role can be fulfilled by any old wire.
If you have a wire carrying lots of current, you may need to make it as big as possible. My computer motherboard has a power rail that is about 5cm wide. Yes - the rail is as wide as the CPU. The ground plane on the other side is just as big. But the shape is not so important. They are big copper squares.
If you have an important signal you may need to carefully design the shape of the wire to make its properties consistent for the electrical signals to reduce signal distortion. If you look at a circuit board with, for example, PCI Express or USB 3 or 10G Ethernet, you may see pairs of tracks with no sharp corners, only smooth curves, and a big gap away from any other tracks. Those tracks carry very delicate very-high-speed data signals. Computer memory busses provide a slightly different example: the tracks do not necessarily follow smooth curves, because the wiring is very short and there is not much room for interference to happen in the first place, but they follow zigzag patterns because it is important that it takes the current exactly the same amount of time to go through each wire.
In radio broadcasting they have wiring that is both high-current and reasonably sensitive, to get 100kW of radio power from the transmitter amplifier up to the antenna. For this they have to use very special types of wiring, such as a metal pipe with another pipe maintained in the center with spacers and the empty space filled with nitrogen gas. 99% of people won't ever encounter these in an electronics career.
Note that the relevant difference is "power" and "signal". "Rail" vs "line" is not important, although it may convey some vague information anyway, just like "lane" vs "road". "Power line" is often used and obvious, but I've never heard of a "signal rail", just like I've heard of neighbourhood streets but never heard of interstate bike lanes.
This answer is written about PCBs. You are working on chips where the constraints are different (e.g. not so important to avoid signal reflections, because the wires are so damn small that the reflections are so fast they don't matter).