This, typically, means the signal is active low. That is, when the signal is 0, it is asserted. This is often written as a bar over the signal name, but the schematic capture tool might not be able to render this.
A common example is a reset pin - when this is 0, the component is held in reset. You might see this on the schematic as:
nRESET example, the
n signifies the active low semantic.
The driving source must have the correct semantic. If it does not, you need to invert it yourself - either a simple MOSFET/transistor or, for larger counts like this, a NOT gate (e.g. a 4049) may well be more space and BOM efficient.