This is actually a rather straightforward calculation, but you might need more data than
Wikipedia says LiPo has a 5%/month self-discharge rate, so even with zero current draw you have 20 months standby. 5%/month * 100mAh is about 7 uA current draw.
So we'll say the combined discharge at 10 uA is 17uA. 100mAh / 17uA = 5900 hours standby time. This is about eight months. Is this sufficient for you? If you knock your standby down to 3uA you can get about a year standby.
Notice that all these calculations are assuming a lot of things. You won't always be in standby mode if your circuit does something useful, so you should add in active current * duty cycle. And of course battery chemistry is complicated, so these are just ballpark figures until you actually build and measure the circuit.