I am now designing one four layer analog board for 24-bits ADC based bio-potential signal acquisition. I have ground and power plane on the second and third layers. Most of the analog signal traces are on the top layer. The ground plane is on the second layer.
The frequency of the board is about 1.5Hz to 3.79kHz. Board size is about 4"x5". The ADC I am using is the ADS1298 from TI, with analog front-end by op-amps and instrumentation amplifier.
My question is should I pour ground on the open area of top and bottom layers? Will that do anything good to the signals? or that will make them worse?