I know potential is always about difference so you can't just measure a potential but it's difference with some other potential.
Let's say I have a GND and two inputs each one 0-5v and I have a ADC measuring 0-1V being 0.0 v == GND. I can't change the reference.
I want to amplify small differences between the inputs and measure the difference with the maximum resolution. Is there an easy way to subtract V1 - V2 and supply the result to the ADC?