We had this topic discussed here many times. It has nothing to do with lead what-so-ever since the temperature of a solder iron is nowhere near hot enough to vaporize any of the metals involved - in which case you would be melting the components as well. Soldering is not welding.
Whenever you do any form of professional soldering, you always need a solder fume extractor, which are devices that come in various shapes and sizes. Often it is a hose of some kind which you fix near the solder area, which vacuums out the harmful gasses away from your face and into some manner of filter.
Just using some DIY fan is not recommended. Holding your breath is not recommended.
The sole purpose of this is to extract vaporized flux and other chemicals from the solder core. These gasses are harmful and can cause various allergies and respiratory problems. RoHS solder is more unhealthy since it melts at approximately 30°C higher temperature than leaded solder, which in turn means more vaporized flux. RoHS was sadly never meant to protect the PCBA assembly operator from chemicals.
Additionally, touching the plastic parts of some connector by accident with your tip happens now and then, even to veterans. There's no healthy gasses coming out of that either.
It is particularly unhealthy to do repair work on PCBA which were covered in conformal coating, glue, silicone or similar. Then a fume extractor is not enough, you need to do such work inside a chemistry hood. Remove as much of the chemicals as possible with isopropyl, then use plenty of external flux. And don't use your finest solder tip...
Soldering is an industrial process, so you need to wash your hands after soldering. Lead is only harmful if you manage to get it in your mouth. And for this reason you shouldn't do soldering in the living areas of your home, getting solder splatter on the floor where small children or pets might be exposed to it.