I am unsure which option is best practice from those featured in the title. This is part of some VLSI coursework I am doing in Cadence and so will need to do the layout of this design as well.
For example, if I have 5 inputs and I only want a high output when each is high - is it best to create a 5-input NAND gate (from 5 PMOS and 5 NMOS transistors) or link together 3 2-input NAND gates?
Logically, the 5-input NAND gate uses fewer transistores but will result in wider pMOSFET channels
Thanks in advance